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Antigen-specific cytotoxicity by invariant NKT cells in vivo is CD95/CD178 dependent and is correlated with antigenic potency

Invariant NKT (iNKT) cells are a unique subset of T lymphocytes that rapidly carry out effector functions following activation with glycolipid Ags, such as the model Ag α-galactosylceramide (αGalCer). Numerous studies have investigated the mechanisms leading to T(h)1- and T(h)2 cytokine production b...

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Bibliografische gegevens
Hoofdauteurs: Wingender, Gerhard, Krebs, Philippe, Beutler, Bruce, Kronenberg, Mitchell
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989418/
https://ncbi.nlm.nih.gov/pubmed/20660713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001018
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