Caspase-mediated Cleavage of RNA-binding Protein HuR Regulates c-Myc Protein Expression after Hypoxic Stress

Altered expression of RNA-binding proteins modulates gene expression in association with mRNAs encoding many proto-oncogenes, cytokines, chemokines, and proinflammatory factors. Hu antigen R (HuR), a ubiquitously expressed protein, controls a range of cellular functions such as tumor progression, ap...

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Bibliografiske detaljer
Main Authors: Talwar, Sudha, Jin, Junfei, Carroll, Brittany, Liu, Angen, Gillespie, Marion Boyd, Palanisamy, Viswanathan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173192/
https://ncbi.nlm.nih.gov/pubmed/21795698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.255927
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