Crystal Structures of Bacterial Peptidoglycan Amidase AmpD and an Unprecedented Activation Mechanism

AmpD is a cytoplasmic peptidoglycan (PG) amidase involved in bacterial cell-wall recycling and in induction of β-lactamase, a key enzyme of β-lactam antibiotic resistance. AmpD belongs to the amidase_2 family that includes zinc-dependent amidases and the peptidoglycan-recognition proteins (PGRPs), h...

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Hlavní autoři: Carrasco-López, Cesar, Rojas-Altuve, Alzoray, Zhang, Weilie, Hesek, Dusan, Lee, Mijoon, Barbe, Sophie, André, Isabelle, Ferrer, Pilar, Silva-Martin, Noella, Castro, German R., Martínez-Ripoll, Martín, Mobashery, Shahriar, Hermoso, Juan A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173140/
https://ncbi.nlm.nih.gov/pubmed/21775432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.264366
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