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Ribonucleotide Discrimination and Reverse Transcription by the Human Mitochondrial DNA Polymerase
During DNA synthesis, DNA polymerases must select against ribonucleotides, present at much higher levels compared with deoxyribonucleotides. Most DNA polymerases are equipped to exclude ribonucleotides from their active site through a bulky side chain residue that can sterically block the 2′-hydroxy...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Biochemistry and Molecular Biology
2011
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173122/ https://ncbi.nlm.nih.gov/pubmed/21778232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.252460 |
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