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Enhancement by LDL of transfer of L-4F and oxidized lipids to HDL in C57BL/6J mice and human plasma

The apoA-I mimetic peptide L-4F [(Ac-D-W-F-K-A-F-Y-D-K-V-A-E-K-F-K-E-A-F-NH2) synthesized from all L-amino acids] has shown potential for the treatment of a variety of diseases. Here, we demonstrate that LDL promotes association between L-4F and HDL. A 2- to 3-fold greater association of L-4F with h...

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Detalhes bibliográficos
Main Authors: Meriwether, David, Imaizumi, Satoshi, Grijalva, Victor, Hough, Greg, Vakili, Ladan, Anantharamaiah, G. M., Farias-Eisner, Robin, Navab, Mohamad, Fogelman, Alan M., Reddy, Srinivasa T., Shechter, Ishaiahu
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173006/
https://ncbi.nlm.nih.gov/pubmed/21804067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M016741
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