Evaluation of Lynch syndrome modifier genes in 748 MMR mutation carriers

Several studies have reported that, in Lynch syndrome resulting from mutations of the mismatch repair (MMR) genes, a CA repeat ≤17 within the IGF1 promoter, SNPs within the xenobiotic metabolizing enzyme gene CYP1A1 and SNPs on 8q23.3 and 11q23.1 modify colorectal cancer (CRC) risk in MMR mutation c...

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Hlavní autoři: Houlle, Solene, Charbonnier, Françoise, Houivet, Estelle, Tinat, Julie, Buisine, Marie-Pierre, Caron, Olivier, Benichou, Jacques, Baert-Desurmont, Stéphanie, Frebourg, Thierry
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172927/
https://ncbi.nlm.nih.gov/pubmed/21407259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.44
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