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Oncogenic AKTivation of translation as a therapeutic target

The AKT signalling pathway is a major regulator of protein synthesis that impinges on multiple cellular processes frequently altered in cancer, such as proliferation, cell growth, survival, and angiogenesis. AKT controls protein synthesis by regulating the multistep process of mRNA translation at ev...

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Detaylı Bibliyografya
Asıl Yazarlar: Hsieh, A C, Truitt, M L, Ruggero, D
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172900/
https://ncbi.nlm.nih.gov/pubmed/21772331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.241
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