Hypoxia-inducible factor-1 drives annexin A2 system-mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice

Oxygen-induced retinopathy (OIR) is a well-characterized model for retinopathy of prematurity, a disorder that results from rapid microvascular proliferation after exposure of the retina to high oxygen levels. Here, we report that the proliferative phase of OIR requires transcriptional induction of...

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Detalhes bibliográficos
Main Authors: Huang, Bihui, Deora, Arun B., He, Kai-Li, Chen, Kang, Sui, Guangzhi, Jacovina, Andrew T., Almeida, Dena, Hong, Peng, Burgman, Paul, Hajjar, Katherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172807/
https://ncbi.nlm.nih.gov/pubmed/21788340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-341214
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