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Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2–dependent fibrinolysis
When plasma levels of homocysteine (HC), a thiol amino acid formed upon methionine demethylation, exceed 12 μM, individuals are at increased risk of developing large vessel atherothrombosis and small vessel dysfunction. The annexin A2 complex (termed “A2”) is the cell surface coreceptor for plasmino...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2769184/ https://ncbi.nlm.nih.gov/pubmed/19841537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39591 |
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