Thrombomodulin is a determinant of metastasis through a mechanism linked to the thrombin binding domain but not the lectin-like domain

Thrombomodulin (TM) is a predominantly endothelial transmembrane glycoprotein that modulates hemostatic function through a domain that controls thrombin-mediated proteolysis and an N-terminal lectin-like domain that controls inflammatory processes. To test the hypothesis that TM is a determinant of...

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Hlavní autoři: Horowitz, Netanel A., Blevins, Elizabeth A., Miller, Whitney M., Perry, Ashley R., Talmage, Kathryn E., Mullins, Eric S., Flick, Matthew J., Queiroz, Karla C. S., Shi, Kun, Spek, C. Arnold, Conway, Edward M., Monia, Brett P., Weiler, Hartmut, Degen, Jay L., Palumbo, Joseph S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2011
Témata:
Thrombosis and Hemostasis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172805/
https://ncbi.nlm.nih.gov/pubmed/21788337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-341222
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