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NK cell education after allogeneic transplantation: dissociation between recovery of cytokine-producing and cytotoxic functions

Natural killer (NK) cells mediate GVL effects after allogeneic hematopoietic cell transplantation (allo-HCT) by the production of inflammatory cytokines and by direct target lysis. The acquisition of both functions was presumed to be developmentally linked, but this linkage remained unstudied after...

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Autors principals: Foley, Bree, Cooley, Sarah, Verneris, Michael R., Curtsinger, Julie, Luo, Xianghua, Waller, Edmund K., Weisdorf, Daniel J., Miller, Jeffrey S.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172795/
https://ncbi.nlm.nih.gov/pubmed/21757615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-347070
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