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Evolution of phage with chemically ambiguous proteomes

BACKGROUND: The widespread introduction of amino acid substitutions into organismal proteomes has occurred during natural evolution, but has been difficult to achieve by directed evolution. The adaptation of the translation apparatus represents one barrier, but the multiple mutations that may be req...

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Pubblicato in:BMC Evol Biol
Autori principali: Bacher, Jamie M, Bull, James J, Ellington, Andrew D
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317279/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14667253/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2148-3-24
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