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Evolution of phage with chemically ambiguous proteomes

BACKGROUND: The widespread introduction of amino acid substitutions into organismal proteomes has occurred during natural evolution, but has been difficult to achieve by directed evolution. The adaptation of the translation apparatus represents one barrier, but the multiple mutations that may be req...

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Veröffentlicht in:BMC Evol Biol
Hauptverfasser: Bacher, Jamie M, Bull, James J, Ellington, Andrew D
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2003
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317279/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14667253/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2148-3-24
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