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The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families

The Elongin BC complex was identified initially as a positive regulator of RNA polymerase II (Pol II) elongation factor Elongin A and subsequently as a component of the multiprotein von Hippel-Lindau (VHL) tumor suppressor complex, in which it participates in both tumor suppression and negative regu...

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Publicat a:Genes Dev
Autors principals: Kamura, Takumi, Sato, Shigeo, Haque, Dewan, Liu, Li, Kaelin, William G., Conaway, Ronald C., Conaway, Joan Weliky
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317264/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9869640/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.24.3872
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