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Serine metabolism: some tumors take the road less traveled
Cancer cells display a reprogramming of metabolism that facilitates growth but addicts them to key enzyme activities. Two studies in Nature and Nature Genetics find that the gene encoding the serine biosynthetic enzyme phosphoglycerate dehydrogenase (PHGDH) is amplified in a subset of cancers and co...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3172581/ https://ncbi.nlm.nih.gov/pubmed/21907134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.08.004 |
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