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Dynamic regulation of PCNA ubiquitylation/deubiquitylation

Proliferating Cell Nuclear Antigen (PCNA) ubiquitylation plays a crucial role in maintaining genomic stability during DNA replication. DNA damage stalling the DNA replication fork induces PCNA ubiquitylation that activates DNA damage bypass to prevent the collapse of DNA replication forks that could...

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Bibliographic Details
Main Authors: Fox, Jennifer T., Lee, Kyoo-young, Myung, Kyungjae
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172383/
https://ncbi.nlm.nih.gov/pubmed/21640107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.05.053
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