Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation

Ligand-dependent activation of gene transcription by nuclear receptors is dependent on the recruitment of coactivators, including a family of related NCoA/SRC factors, via a region containing three helical domains sharing an LXXLL core consensus sequence, referred to as LXDs. In this manuscript, we...

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Main Authors: McInerney, Eileen M., Rose, David W., Flynn, Sarah E., Westin, Stefan, Mullen, Tina-Marie, Krones, Anna, Inostroza, Juan, Torchia, Joseph, Nolte, Robert T., Assa-Munt, Nuria, Milburn, Michael V., Glass, Christopher K., Rosenfeld, Michael G.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1998
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC317227/
https://ncbi.nlm.nih.gov/pubmed/9808623
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