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Remodelling of Cortical Actin Where Lytic Granules Dock at Natural Killer Cell Immune Synapses Revealed by Super-Resolution Microscopy

Natural Killer (NK) cells are innate immune cells that secrete lytic granules to directly kill virus-infected or transformed cells across an immune synapse. However, a major gap in understanding this process is in establishing how lytic granules pass through the mesh of cortical actin known to under...

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Detalhes bibliográficos
Main Authors: Brown, Alice C. N., Oddos, Stephane, Dobbie, Ian M., Alakoskela, Juha-Matti, Parton, Richard M., Eissmann, Philipp, Neil, Mark A. A., Dunsby, Christopher, French, Paul M. W., Davis, Ilan, Davis, Daniel M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172219/
https://ncbi.nlm.nih.gov/pubmed/21931537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001152
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