Luciferase-Expressing Leishmania infantum Allows the Monitoring of Amastigote Population Size, In Vivo, Ex Vivo and In Vitro

Here we engineered transgenic Leishmania infantum that express luciferase, the objectives being to more easily monitor in real time their establishment either in BALB/c mice—the liver and spleen being mainly studied—or in vitro. Whatever stationary phase L. infantum promastigotes population—wild typ...

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Main Authors: Michel, Grégory, Ferrua, Bernard, Lang, Thierry, Maddugoda, Madhavi P., Munro, Patrick, Pomares, Christelle, Lemichez, Emmanuel, Marty, Pierre
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172198/
https://ncbi.nlm.nih.gov/pubmed/21931877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001323
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