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Luciferase-Expressing Leishmania infantum Allows the Monitoring of Amastigote Population Size, In Vivo, Ex Vivo and In Vitro

Here we engineered transgenic Leishmania infantum that express luciferase, the objectives being to more easily monitor in real time their establishment either in BALB/c mice—the liver and spleen being mainly studied—or in vitro. Whatever stationary phase L. infantum promastigotes population—wild typ...

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Bibliographic Details
Main Authors: Michel, Grégory, Ferrua, Bernard, Lang, Thierry, Maddugoda, Madhavi P., Munro, Patrick, Pomares, Christelle, Lemichez, Emmanuel, Marty, Pierre
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172198/
https://ncbi.nlm.nih.gov/pubmed/21931877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001323
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