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ATR-mediated phosphorylation of DNA polymerase η is needed for efficient recovery from UV damage
DNA polymerase η (polη) belongs to the Y-family of DNA polymerases and facilitates translesion synthesis past UV damage. We show that, after UV irradiation, polη becomes phosphorylated at Ser601 by the ataxia-telangiectasia mutated and Rad3-related (ATR) kinase. DNA damage–induced phosphorylation of...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3172178/ https://ncbi.nlm.nih.gov/pubmed/21242293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201008076 |
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