Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development

Cell cycle exit is required for terminal differentiation of many cell types. The retinoblastoma protein Rb has been implicated both in cell cycle exit and differentiation in several tissues. Rb is negatively regulated by cyclin-dependent kinases (Cdks). The main effectors that down-regulate Cdk acti...

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Pubblicato in:	Genes Dev
Autori principali:	Zhang, Pumin, Wong, Calvin, DePinho, Ronald A., Harper, J. Wade, Elledge, Stephen J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 1998
Soggetti:	Research Communication
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317217/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9784491/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.20.3162
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