mRNA stabilization by poly(A) binding protein is independent of poly(A) and requires translation

Translation and mRNA stability are enhanced by the presence of a poly(A) tail. In vivo, the tail interacts with a conserved polypeptide, poly(A) binding protein (Pab1p). To examine Pab1p function in vivo, we have tethered Pab1p to the 3′ UTR of reporter mRNAs by fusing it to MS2 coat protein and pla...

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Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Genes Dev
Prif Awduron:	Coller, Jeffery M., Gray, Nicola K., Wickens, Marvin P.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Cold Spring Harbor Laboratory Press 1998
Pynciau:	Research Paper
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317214/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9784497/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.20.3226
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