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Autophagy, and BiP level decrease are early key events in retrograde degeneration of motoneurons
Disconnection of the axon from the soma of spinal motoneurons (MNs) leads either to a retrograde degenerative process or to a regenerative reaction, depending on the severity and the proximity to the soma of the axonal lesion. The endoplasmic reticulum (ER) is a continuous membranous network that ex...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3172115/ https://ncbi.nlm.nih.gov/pubmed/21436843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.24 |
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