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Autophagy, and BiP level decrease are early key events in retrograde degeneration of motoneurons

Disconnection of the axon from the soma of spinal motoneurons (MNs) leads either to a retrograde degenerative process or to a regenerative reaction, depending on the severity and the proximity to the soma of the axonal lesion. The endoplasmic reticulum (ER) is a continuous membranous network that ex...

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Detalhes bibliográficos
Main Authors: Penas, C, Font-Nieves, M, Forés, J, Petegnief, V, Planas, A, Navarro, X, Casas, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172115/
https://ncbi.nlm.nih.gov/pubmed/21436843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.24
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