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Wnt signaling in Xenopus embryos inhibits Bmp4 expression and activates neural development

We report a new role for Wnt signaling in the vertebrate embryo: the induction of neural tissue from ectoderm. Early expression of mouse wnt8, Xwnt8, β-catenin, or dominant-negative GSK3 induces the expression of neural-specific markers and inhibits the expression of Bmp4 in Xenopus ectoderm. We sho...

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Bibliografische gegevens
Hoofdauteurs: Baker, Julie C., Beddington, Rosa S.P., Harland, Richard M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 1999
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC317181/
https://ncbi.nlm.nih.gov/pubmed/10601040
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