Wnt signaling in Xenopus embryos inhibits Bmp4 expression and activates neural development

We report a new role for Wnt signaling in the vertebrate embryo: the induction of neural tissue from ectoderm. Early expression of mouse wnt8, Xwnt8, β-catenin, or dominant-negative GSK3 induces the expression of neural-specific markers and inhibits the expression of Bmp4 in Xenopus ectoderm. We sho...

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Bibliografiske detaljer

Udgivet i:	Genes Dev
Principais autores:	Baker, Julie C., Beddington, Rosa S.P., Harland, Richard M.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Cold Spring Harbor Laboratory Press 1999
Fag:	Research Paper
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317181/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10601040/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.23.3149
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