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CHEMICAL GENETICS: LIGAND-BASED DISCOVERY OF GENE FUNCTION
Chemical genetics is the study of gene-product function in a cellular or organismal context using exogenous ligands. In this approach, small molecules that bind directly to proteins are used to alter protein function, enabling a kinetic analysis of the in vivo consequences of these changes. Recent a...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171795/ https://ncbi.nlm.nih.gov/pubmed/11253651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/35038557 |
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