Genetically Encoded Fragment-Based Discovery of Glycopeptide Ligands for Carbohydrate-Binding Proteins

We describe an approach to accelerate the search for competitive inhibitors for carbohydrate-recognition domains (CRDs). Genetically encoded fragment-based discovery (GE-FBD) uses selection of phage-displayed glycopeptides to dock a glycan fragment at the CRD and guide selection of synergistic pepti...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Ng, Simon, Lin, Edith, Kitov, Pavel I., Tjhung, Katrina F., Gerlits, Oksana O., Deng, Lu, Kasper, Brian, Sood, Amika, Paschal, Beth M., Zhang, Ping, Ling, Chang-Chun, Klassen, John S., Noren, Christopher J., Mahal, Lara K., Woods, Robert J., Coates, Leighton, Derda, Ratmir
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553193/
https://ncbi.nlm.nih.gov/pubmed/25860443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja511237n
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados