Altered DNA-binding specificity mutants of EKLF and Sp1 show that EKLF is an activator of the β-globin locus control region in vivo

The locus control region of the β-globin cluster contains five DNase I hypersensitive sites (5′HS1–5) required for locus activation. 5′HS3 contains six G-rich motifs that are essential for its activity. Members of a protein family, characterized by three zinc fingers highly homologous to those found...

詳細記述

書誌詳細

出版年:	Genes Dev
主要な著者:	Gillemans, Nynke, Tewari, Rita, Lindeboom, Fokke, Rottier, Robbert, de Wit, Ton, Wijgerde, Mark, Grosveld, Frank, Philipsen, Sjaak
フォーマット:	Artigo
言語:	Inglês
出版事項:	Cold Spring Harbor Laboratory Press 1998
主題:	Research Paper
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317172/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9744863/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.18.2863
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!