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The interface of σ with core RNA polymerase is extensive, conserved, and functionally specialized

The σ subunit of eubacterial RNA polymerase is required throughout initiation, but how it communicates with core polymerase (α(2)ββ′) is poorly understood. The present work addresses the location and function of the interface of σ with core. Our studies suggest that this interface is extensive as mu...

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Detalhes bibliográficos
Main Authors: Sharp, Meghan M., Chan, Cathleen L., Lu, Chi Zen, Marr, Michael T., Nechaev, Sergei, Merritt, Ernest W., Severinov, Konstantin, Roberts, Jeffrey W., Gross, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC317155/
https://ncbi.nlm.nih.gov/pubmed/10580008
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