An Image Driven Systems Biology Approach for Neurodegenerative Disease Studies in the TSC-mTOR Pathway

In this brief paper we present an overview of the TSC-mTOR pathway and its importance in neurodegenerative disease (ND). We illustrate the influence of ND on dendritic spine morphology. Then we discuss some details of functional gene networks (FGN) and use this information to propose an image driven...

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Hlavní autoři: Beck, Dominik, Zhou, Xiaobo, Pham, Tuan, Sabatini, Bernardo, Wong, Stephen T.C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171509/
https://ncbi.nlm.nih.gov/pubmed/21922078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/LISSA.2009.4906703
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