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Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses

Placental development is profoundly influenced by oxygen (O(2)) tension. Human cytotrophoblasts proliferate in vitro under low O(2) conditions but differentiate at higher O(2) levels, mimicking the developmental transition they undergo as they invade the placental bed to establish the maternal–fetal...

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Autors principals: Adelman, David M., Gertsenstein, Marina, Nagy, Andras, Simon, M. Celeste, Maltepe, Emin
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC317149/
https://ncbi.nlm.nih.gov/pubmed/11124810
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