MiR-34a Targeting of Notch Ligand Delta-Like 1 Impairs CD15(+)/CD133(+) Tumor-Propagating Cells and Supports Neural Differentiation in Medulloblastoma

BACKGROUND: Through negative regulation of gene expression, microRNAs (miRNAs) can function as oncosuppressors in cancers, and can themselves show altered expression in various tumor types. Here, we have investigated medulloblastoma tumors (MBs), which arise from an early impairment of developmental...

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Главные авторы: de Antonellis, Pasqualino, Medaglia, Chiara, Cusanelli, Emilio, Andolfo, Immacolata, Liguori, Lucia, De Vita, Gennaro, Carotenuto, Marianeve, Bello, Annamaria, Formiggini, Fabio, Galeone, Aldo, De Rosa, Giuseppe, Virgilio, Antonella, Scognamiglio, Immacolata, Sciro, Manuela, Basso, Giuseppe, Schulte, Johannes H., Cinalli, Giuseppe, Iolascon, Achille, Zollo, Massimo
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171461/
https://ncbi.nlm.nih.gov/pubmed/21931765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024584
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