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D-β-Hydroxybutyrate Is Protective in Mouse Models of Huntington's Disease
Abnormalities in mitochondrial function and epigenetic regulation are thought to be instrumental in Huntington's disease (HD), a fatal genetic disorder caused by an expanded polyglutamine track in the protein huntingtin. Given the lack of effective therapies for HD, we sought to assess the neur...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171454/ https://ncbi.nlm.nih.gov/pubmed/21931779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024620 |
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