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Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gβγ complex underlies activation of the yeast pheromone response pathway

In the Saccharomyces cerevisiae pheromone response pathway, the Gβγ complex activates downstream responses by an unknown mechanism involving a MAP kinase cascade, the PAK-like kinase Ste20, and a Rho family GTPase, Cdc42. Here we show that Gβγ must remain membrane-associated after release from Gα to...

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Autores principales: Pryciak, Peter M., Huntress, Frederick A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC317142/
https://ncbi.nlm.nih.gov/pubmed/9732267
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