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Membrane localization of scaffold proteins promotes graded signaling in the yeast MAP kinase cascade

BACKGROUND: Signaling through mitogen-activated protein kinase (MAPK) cascade pathways can show various input-output behaviors, including either switch-like or graded responses to increasing levels of stimulus. Prior studies suggest that switch-like behavior is promoted by positive feedback loops an...

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Detalhes bibliográficos
Main Authors: Takahashi, Satoe, Pryciak, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562168/
https://ncbi.nlm.nih.gov/pubmed/18722124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.07.050
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