Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants

Telomerase is a ribonucleoprotein complex that adds telomeric DNA repeats to the ends of most eukaryotic chromosomes. The reverse transcriptase subunit of telomerase (TERT) differs from retroviral reverse transcriptases in having a long basic amino-terminal extension. We made a large library contain...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Friedman, Katherine L., Cech, Thomas R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 1999
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317136/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10557213/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.21.2863
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