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Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants

Telomerase is a ribonucleoprotein complex that adds telomeric DNA repeats to the ends of most eukaryotic chromosomes. The reverse transcriptase subunit of telomerase (TERT) differs from retroviral reverse transcriptases in having a long basic amino-terminal extension. We made a large library contain...

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Detalhes bibliográficos
Main Authors: Friedman, Katherine L., Cech, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC317136/
https://ncbi.nlm.nih.gov/pubmed/10557213
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