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Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity

NK cells are a major component of the antitumor immune response and are involved in controlling tumor progression and metastases in animal models. Here, we show that dysfunction of these cells accompanies human breast tumor progression. We characterized human peripheral blood NK (p-NK) cells and mal...

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Autores principales: Mamessier, Emilie, Sylvain, Aude, Thibult, Marie-Laure, Houvenaeghel, Gilles, Jacquemier, Jocelyne, Castellano, Rémy, Gonçalves, Anthony, André, Pascale, Romagné, François, Thibault, Gilles, Viens, Patrice, Birnbaum, Daniel, Bertucci, François, Moretta, Alessandro, Olive, Daniel
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171102/
https://ncbi.nlm.nih.gov/pubmed/21841316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45816
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