Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity

NK cells are a major component of the antitumor immune response and are involved in controlling tumor progression and metastases in animal models. Here, we show that dysfunction of these cells accompanies human breast tumor progression. We characterized human peripheral blood NK (p-NK) cells and mal...

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Detalhes bibliográficos
Main Authors: Mamessier, Emilie, Sylvain, Aude, Thibult, Marie-Laure, Houvenaeghel, Gilles, Jacquemier, Jocelyne, Castellano, Rémy, Gonçalves, Anthony, André, Pascale, Romagné, François, Thibault, Gilles, Viens, Patrice, Birnbaum, Daniel, Bertucci, François, Moretta, Alessandro, Olive, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171102/
https://ncbi.nlm.nih.gov/pubmed/21841316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45816
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