Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma

New anticancer drugs that target oncogenic signaling molecules have greatly improved the treatment of certain cancers. However, resistance to targeted therapeutics is a major clinical problem and the redundancy of oncogenic signaling pathways provides back-up mechanisms that allow cancer cells to es...

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Библиографические подробности
Главные авторы: Schatz, Jonathan H., Oricchio, Elisa, Wolfe, Andrew L., Jiang, Man, Linkov, Irina, Maragulia, Jocelyn, Shi, Weiji, Zhang, Zhigang, Rajasekhar, Vinagolu K., Pagano, Nen C., Porco, John A., Teruya-Feldstein, Julie, Rosen, Neal, Zelenetz, Andrew D., Pelletier, Jerry, Wendel, Hans-Guido
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2011
Предметы:
Brief Definitive Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171093/
https://ncbi.nlm.nih.gov/pubmed/21859846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110846
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