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Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation
Nuclear factor (NF)-κB, activated by IκB kinase (IKK), is a key regulator of inflammation, innate immunity, and tissue integrity. NF-κB and one of its main activators and transcriptional targets, tumor necrosis factor (TNF), are up-regulated in many inflammatory diseases that are accompanied by tiss...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171091/ https://ncbi.nlm.nih.gov/pubmed/21825016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110242 |
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