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NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses

The canonical NF-κB pathway is a driving force for virtually all aspects of inflammation. Conversely, the role of the noncanonical NF-κB pathway and its central mediator NF-κB–inducing kinase (NIK) remains poorly defined. NIK has been proposed to be involved in the formation of T(H)17 cells, and its...

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Detalhes bibliográficos
Main Authors: Hofmann, Janin, Mair, Florian, Greter, Melanie, Schmidt-Supprian, Marc, Becher, Burkhard
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171087/
https://ncbi.nlm.nih.gov/pubmed/21807870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110128
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