Wnt–β-catenin–Tcf-4 signalling-modulated invasiveness is dependent on osteopontin expression in breast cancer

BACKGROUND: We have previously demonstrated that Tcf-4 regulates osteopontin (OPN) in rat breast epithelial cells, Rama37. In this report, we have examined the importance of this regulation in human breast cancer. METHODS: The regulatory roles of Tcf-4 on cell invasion and OPN expression were invest...

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Dades bibliogràfiques
Autors principals: Ravindranath, A, Yuen, H-F, Chan, K-K, Grills, C, Fennell, D A, Lappin, T R, El-Tanani, M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
Matèries:
Molecular Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170969/
https://ncbi.nlm.nih.gov/pubmed/21772333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.269
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