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Mitochondrial recoupling: a novel therapeutic strategy for cancer?
Recent findings link metabolic transformation of cancer cells to aberrant functions of mitochondrial uncoupling proteins (UCPs). By inducing proton leak, UCPs interfere with mitochondrial synthesis of adenosine 5′-triphosphate, which is also a key determinant of glycolytic pathways. In addition, UCP...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3170958/ https://ncbi.nlm.nih.gov/pubmed/21712825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.245 |
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