Mitochondrial recoupling: a novel therapeutic strategy for cancer?

Recent findings link metabolic transformation of cancer cells to aberrant functions of mitochondrial uncoupling proteins (UCPs). By inducing proton leak, UCPs interfere with mitochondrial synthesis of adenosine 5′-triphosphate, which is also a key determinant of glycolytic pathways. In addition, UCP...

Full description

Saved in:
Bibliographic Details
Main Authors: Baffy, G, Derdak, Z, Robson, S C
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
Subjects:
Minireview
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170958/
https://ncbi.nlm.nih.gov/pubmed/21712825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.245
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items