Cap methyltransferase selective binding and methylation of GpppG-RNA are stimulated by importin-α

We screened a human cDNA library for proteins that bind mRNA cap methyltransferase (MT) and isolated nuclear transporter importin-α (Impα). This direct association was confirmed by glutathione S-transferase (GST) pulldown, coimmunoprecipitation, and nuclear colocalization. In gel shift assays, MT se...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Genes Dev
Principais autores:	Wen, Yingxia, Shatkin, Aaron J.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Cold Spring Harbor Laboratory Press 2000
Fag:	Research Communication
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317093/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11114884/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.848200
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!