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PI3Kγ Mediates Kaposi’s Sarcoma Associated Herpesvirus vGPCR-Induced Sarcomagenesis
Angioproliferative tumors induced by the Kaposi’s Sarcoma associated herpesvirus (KSHV) have been successfully treated with rapamycin, which provided direct evidence of the clinical activity of mTOR inhibitors in human malignancies. However, prolonged mTOR inhibition may raise concerns in immunocomp...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3170773/ https://ncbi.nlm.nih.gov/pubmed/21665152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.05.005 |
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