UPLC-MS-based Urine Metabolomics Reveals Indole-3-lactic acid and Phenyllactic acid as Conserved Biomarkers for Alcohol-induced Liver Disease in the Ppara-null Mouse Model

Since the development and prognosis of alcohol-induced liver disease (ALD) vary significantly with genetic background, identification of a genetic background-independent noninvasive ALD biomarker would significantly improve screening and diagnosis. This study explored the effect of genetic backgroun...

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Hlavní autoři: Manna, Soumen K., Patterson, Andrew D., Yang, Qian, Krausz, Kristopher W., Idle, Jeffrey R., Fornace, Albert J., Gonzalez, Frank J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170755/
https://ncbi.nlm.nih.gov/pubmed/21749142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr200310s
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