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Multilineage embryonic hematopoiesis requires hypoxic ARNT activity

Although most cells undergo growth arrest during hypoxia, endothelial cells and placental cytotrophoblasts proliferate in response to low O(2). We demonstrate that proliferation of embryonic multilineage hematopoietic progenitors is also regulated by a hypoxia-mediated signaling pathway. This pathwa...

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Autors principals: Adelman, David M., Maltepe, Emin, Simon, M. Celeste
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC317070/
https://ncbi.nlm.nih.gov/pubmed/10521392
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