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Computed structures of point deletion mutants and their enzymatic activities
Point deletions in enzymes can vary in effect from negligible to complete loss of activity, however, these effects are not generally predictable. Deletions are widely observed in nature and often result in diseases such as cancer, cystic fibrosis, or osteogenesis imperfecta. Here, we have developed...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3170519/ https://ncbi.nlm.nih.gov/pubmed/21905110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23109 |
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